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Keywords:

  • circular dichroism;
  • DNA;
  • electrospray mass spectrometry;
  • G-quadruplexes;
  • nucleic acids
Thumbnail image of graphical abstract

In my (DNA) dreams: A tri-G-quadruplex was constructed from three strands (T1–T3) of DNA using duplex formation to guide the G-rich tracts into close proximity with the addition of Li+ ions (see scheme). The defined G-quadruplex structure was formed upon addition of Na+ ions and characterized by gel electrophoresis and spectroscopy.