D.O’H. thanks the EPSRC and the ERC for an Advanced Investigator Grant to support this research. We thank the EPSRC for a research grant and for financial support through a DTG Studentship (A.J.D.).
The Synthesis of η-1,2,3,4,5,6-Hexafluorocyclohexane (Benzene Hexafluoride) from Benzene†
Article first published online: 11 SEP 2012
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 51, Issue 40, pages 10086–10088, October 1, 2012
How to Cite
Durie, A. J., Slawin, A. M. Z., Lebl, T. and O'Hagan, D. (2012), The Synthesis of η-1,2,3,4,5,6-Hexafluorocyclohexane (Benzene Hexafluoride) from Benzene . Angew. Chem. Int. Ed., 51: 10086–10088. doi: 10.1002/anie.201205577
- Issue published online: 26 SEP 2012
- Article first published online: 11 SEP 2012
- Manuscript Received: 13 JUL 2012
- benzene hexafluoride;
- conformational analysis;
- organofluorine chemistry
Six of the best: Benzene had been used by Faraday and Mitscherlich in their respective synthesis of hexachloro- and hexabromocyclohexane in the early 19th century. Also starting from benzene, η-1,2,3,4,5,6-hexafluorocyclohexane (benzene hexafluoride; see X-ray structure of a dimer) was now synthesized in five steps.