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Keywords:

  • cell detachment;
  • host–guest systems;
  • stimuli responsive;
  • supramolecular chemistry
Thumbnail image of graphical abstract

Please release me: Electrochemically activated cell release is achieved using a redox-active supramolecular complex (see picture). Host molecule CB[8] (green) links surface-bound viologen (purple) with solution-exposed RGD peptides (red). Electrochemical reduction dissociates the complex, releases the peptides, and thus releases the cells from the substrates. This supramolecular strategy is also applicable to microelectrodes.