These authors contributed equally.
pH-Responsive Size-Tunable Self-Assembled DNA Dendrimers†
Article first published online: 4 OCT 2012
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 51, Issue 45, pages 11271–11274, November 5, 2012
How to Cite
Zhou, T., Chen, P., Niu, L., Jin, J., Liang, D., Li, Z., Yang, Z. and Liu, D. (2012), pH-Responsive Size-Tunable Self-Assembled DNA Dendrimers . Angew. Chem. Int. Ed., 51: 11271–11274. doi: 10.1002/anie.201205862
We thank the National Natural Science Foundation of China (No. 20974030, 91027046, 21121004) and the National Basic Research Program of China (973 program, No. 2013CB932803) for financial support.
- Issue published online: 30 OCT 2012
- Article first published online: 4 OCT 2012
- Manuscript Received: 24 JUL 2012
- National Natural Science Foundation of China. Grant Numbers: 20974030, 91027046, 21121004
- National Basic Research Program of China. Grant Number: 2013CB932803
- pH responsiveness;
- size tunable
Putting the DNA in dendrimers: A strategy to swiftly prepare DNA dendrimers based solely on DNA self-assembly is presented. This technique produces highly pure DNA dendrimers with an excellent yield of high generation dendrimers. The incorporation of molecular motors (i-motifs) into the DNA dendrimers allows for a change in size (up to 30%) in response to changing pH values (see scheme).