Dendritic Fluoroalcohols as Catalysts for Alkene Epoxidation with Hydrogen Peroxide


  • Financial support by the Fonds der Chemischen Industrie is gratefully acknowledged. J.K. thanks Henkel KGaA, Düsseldorf, for a doctoral fellowship. A.B. acknowledges COST Membership (CM0905, Organocatalysis). R.H. would like to acknowledge the financial support from the Cluster of Excellence “Unifying Concepts in Catalysis”.


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Cooperativity is the key for mild catalytic epoxidation: The immobilization of fluoroalcohols on dendritic polyglycerol (by “click chemistry”) provides organocatalysts that can form multiple hydrogen bonds. The epoxidation of alkenes with aqueous hydrogen peroxide proceeds efficiently in the presence of dendritic fluoroalcohol catalysts. The supported catalysts can be separated by membrane filtration and reused.