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Keywords:

  • cucurbit[n]uril;
  • host–guest systems;
  • medicinal chemistry;
  • molecular recognition;
  • neuromuscular blocking agents
Thumbnail image of graphical abstract

Be My Guest: Two acyclic cucurbit[n]uril-type receptors that carry SO3-groups bind tightly to several commonly used neuromuscular blocking agents, such as rocuronium, in aqueous solution as revealed by direct and competitive UV/Vis binding assays. One of these containers functions as a potent reversal agent for rocuronium-induced neuromuscular block in rats.