Mild and Homogeneous Cobalt-Catalyzed Hydrogenation of C[DOUBLE BOND]C, C[DOUBLE BOND]O, and C[DOUBLE BOND]N Bonds

Authors

  • Dr. Guoqi Zhang,

    1. Chemistry and Materials Physics Applications Divisions, Los Alamos National Laboratory, MS J582, Los Alamos, NM 87545 (USA)
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  • Dr. Brian L. Scott,

    1. Chemistry and Materials Physics Applications Divisions, Los Alamos National Laboratory, MS J582, Los Alamos, NM 87545 (USA)
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  • Dr. Susan K. Hanson

    Corresponding author
    1. Chemistry and Materials Physics Applications Divisions, Los Alamos National Laboratory, MS J582, Los Alamos, NM 87545 (USA)
    • Chemistry and Materials Physics Applications Divisions, Los Alamos National Laboratory, MS J582, Los Alamos, NM 87545 (USA)
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  • This work was supported by Los Alamos National Laboratory LDRD Early Career Award (20110537ER).

Abstract

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A cationic cobalt(II)–alkyl complex is an effective precatalyst for hydrogenation of alkenes, aldehydes, ketones, and imines under mild conditions (1–4 atm H2; see scheme). The catalyst shows a high functional-group tolerance across a broad range of substrates. Experiments suggest that the active catalytic species is a cobalt(II)–hydride complex.

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