This research was supported in part by the NIH (AI084140, GM032136), BBSRC (BB/G023123/1), and EC (PIEF-GA-2010-275683). J.L.G. thanks the NIH for a postdoctoral fellowship (F32GM10052101). A.G.R. is a Leopoldina-Nationale Akademie der Wissenschaften Postdoctoral Fellow. We are grateful to the beamline scientists of the Proxima-1 beamline at the Soleil synchrotron facility for their assistance.
Small-Molecule Inhibitors of the Interaction between the E3 Ligase VHL and HIF1α†
Article first published online: 12 OCT 2012
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 51, Issue 46, pages 11463–11467, November 12, 2012
How to Cite
Buckley, D. L., Gustafson, J. L., Van Molle, I., Roth, A. G., Tae, H. S., Gareiss, P. C., Jorgensen, W. L., Ciulli, A. and Crews, C. M. (2012), Small-Molecule Inhibitors of the Interaction between the E3 Ligase VHL and HIF1α . Angew. Chem. Int. Ed., 51: 11463–11467. doi: 10.1002/anie.201206231
- Issue published online: 7 NOV 2012
- Article first published online: 12 OCT 2012
- Manuscript Received: 3 AUG 2012
- NIH. Grant Numbers: AI084140, GM032136
- BBSRC. Grant Number: BB/G023123/1
- EC. Grant Number: PIEF-GA-2010-275683
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