We thank the UK EPSRC (grant EP/H01313X/1) and Ministry of Education, Brunei (scholarship to C.S.O.) for support.
A Remarkable Switch from a Diamination to a Hydrohydrazination Catalyst and Observation of an Unprecedented Catalyst Resting State†
Article first published online: 4 NOV 2012
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 51, Issue 49, pages 12298–12302, December 3, 2012
How to Cite
Schwarz, A. D., Onn, C. S. and Mountford, P. (2012), A Remarkable Switch from a Diamination to a Hydrohydrazination Catalyst and Observation of an Unprecedented Catalyst Resting State . Angew. Chem. Int. Ed., 51: 12298–12302. doi: 10.1002/anie.201206249
- Issue published online: 28 NOV 2012
- Article first published online: 4 NOV 2012
- Manuscript Revised: 2 OCT 2012
- Manuscript Received: 3 AUG 2012
- homogeneous catalysis;
- hydrazide complexes;
A small change with a big effect: Reaction of the titanium complex 1 with terminal alkynes gave the unusual acetylide–vinylhydrazide(1−) compounds 2 (R=4-C6H4X (X=Me, CF3, OMe), C6F5, SiMe3) as hydrohydrazination intermediates. In contrast, a complex similar to 1 with bulkier trimethylsilyl substituents in place of the isopropyl groups is known to catalyze the 1,2-diamination of alkynes with hydrazines.