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Keywords:

  • catalysis;
  • nanoparticles;
  • peptides;
  • self-assembly
Thumbnail image of graphical abstract

Inspired by nature: Self-assembled peptide nanoparticles have been designed that accelerate ester hydrolysis (see picture; Cbz=carbobenzyloxy, NP=p-NO2-C6H4). The concerted interplay of the multivalent surface with the catalytically active peptide and the substrate at the same time combines several aspects decisive for the catalyst's efficiency, a property characteristic of enzymes.