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Medication Detection by a Combinatorial Fluorescent Molecular Sensor


  • This research was supported by the Peter and Patricia Gruber Foundation and by the Helen and Martin Kimmel Center for Molecular Design. D.M. is the incumbent of the Judith and Martin Freedman Career Development Chair. We thank Dr. Leila Motiei for fruitful discussions.


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Working together to uncover the truth: A molecule-sized diagnostic system combining several recognition elements and four fluorescence-emission channels enabled the identification of a wide range of pharmaceuticals on the basis of distinct photophysical processes. The molecular sensor (see simplified representation; ID=identification) was also used to analyze drug concentrations and combinations in urine samples in a high-throughput manner.