Defined Hypervalent Iodine(III) Reagents Incorporating Transferable Nitrogen Groups: Nucleophilic Amination through Electrophilic Activation


  • We thank Fundación ICIQ and the Spanish Ministerio de Economía (CTQ2011-25027) for financial support.


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Only I and N: Hypervalent iodine(III) reagents with two reactive I[BOND]N single bonds have been isolated for the first time. Their solid-state and solution structures provide evidence for enhanced electrophilicity at iodine and nucleophilic character of the imine. As a result, improved reactivity in amination reactions and unprecedented nitrogen-transfer reactions under metal-free conditions are realized.