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Keywords:

  • deamination;
  • gene repair;
  • protein modification;
  • RNA;
  • RNA editing
Thumbnail image of graphical abstract

Checking for mistakes: By conjugating a catalytic domain with a guide RNA, deamination activity can be harnessed to repair a specific codon on mRNA. This method can be used for the highly selective repair of point mutations in mRNA by site-selective editing.