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Keywords:

  • analytical methods;
  • C[BOND]C coupling;
  • electrospray;
  • mass spectrometry;
  • microscale synthesis
Thumbnail image of graphical abstract

From analysis towards synthesis: Charged microdroplets act as microreaction vessels, extending the use of electrospray mass spectrometry from chemical analysis to synthesis. Application of this unique reaction conditions allows microscale carbon–carbon bond forming reactions to be performed rapidly and in high yields (see picture).