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Direct Exchange of a Ketone Methyl or Aryl Group to Another Aryl Group through C[BOND]C Bond Activation Assisted by Rhodium Chelation

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  • This work was supported by grants from the NSFC (21072149, 20872108).

Abstract

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Swapped: Commercially available quinolinone derivatives (1 or 2, see scheme) were reacted with arylboronic acids in the presence of a RhI complex to give aryl(quinolin-8-yl)methanone products 3 in medium to good yields. A mechanism that involves the in situ oxidation of RhI to RhIII by O2 in the presence of CuI was proposed.

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