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Keywords:

  • annulation;
  • C[BOND]H functionalization;
  • oxidation;
  • ruthenium;
  • synthetic methods
Thumbnail image of graphical abstract

Ru(de) awakening: The synthesis of carbocycles by the ruthenium-catalyzed oxidative annulation of alkynes with 2-aryl cyclic 1,3-dicarbonyl substrates is described. Proceeding by the functionalization of Cmath image[BOND]H and Cmath image[BOND]H bonds, and the formation of an all-carbon quaternary center, the reaction provides a diverse range of spiroindenes in good yields with high levels of regioselectivity.