Financial support for this research was obtained from the Ministerio de Ciencia e Innovación (Spain) through grants CTQ2009-13797 and CTQ2012-36074. M.D.-L. is grateful for a doctoral grant (BES-2009-029354) from the Ministerio de Ciencia e Innovación (Spain).
Fastest Thermal Isomerization of an Azobenzene for Nanosecond Photoswitching Applications under Physiological Conditions†
Article first published online: 9 NOV 2012
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 51, Issue 51, pages 12820–12823, December 14, 2012
How to Cite
Garcia-Amorós, J., Díaz-Lobo, M., Nonell, S. and Velasco, D. (2012), Fastest Thermal Isomerization of an Azobenzene for Nanosecond Photoswitching Applications under Physiological Conditions . Angew. Chem. Int. Ed., 51: 12820–12823. doi: 10.1002/anie.201207602
- Issue published online: 10 DEC 2012
- Article first published online: 9 NOV 2012
- Manuscript Received: 19 SEP 2012
- Ministerio de Ciencia e Innovación (Spain). Grant Numbers: CTQ2009-13797, CTQ2012-36074, BES-2009-029354
- azo compounds;
- molecular switches;
- nanosecond flash photolysis;
When speed is of the essence: After photoisomerization to its metastable cis form, an azo dye must undergo fast thermal isomerization back to the trans form to be suitable for real-time information transmission. The azopyrimidine shown has a relaxation time (τ) of just 40 ns under physiological conditions, as well as high biocompatibility, as determined by Escherichia coli growth in its presence (see picture).