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Thermoresponsive Dynamic Covalent Single-Chain Polymer Nanoparticles Reversibly Transform into a Hydrogel


  • We thank the Engineering and Physical Sciences Research Council for generous support (EP/G066507/1).


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To gel and back: Polymer nanoparticles can be reversibly transformed into a chemically cross-linked hydrogel. This transformation is triggered by the application of heat, which causes the polymer chains to aggregate, and the dynamic nature of the covalent cross-linking serves to reorganize the polymer chains into a hydrogel network.