Lighting up Carbon Monoxide: Fluorescent Probes for Monitoring CO in Living Cells

Authors

  • Lin Yuan,

    1. State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082 (P.R. China)
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  • Prof. Weiying Lin,

    Corresponding author
    1. State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082 (P.R. China)
    • State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082 (P.R. China)
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  • Li Tan,

    1. State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082 (P.R. China)
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  • Kaibo Zheng,

    1. State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082 (P.R. China)
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  • Weimin Huang

    1. State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082 (P.R. China)
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  • Funding was provided by NSFC (21172063).

Abstract

original image

All aglow: Both a fluorescent biosensor, composed of a circularly permuted yellow fluorescent protein (cpYFP), and a small-molecule fluorescent probe (1) for the detection of CO in living cells have been recently reported. Though different these novel probes were designed based on the unique binding ability of CO to transition-metal ions.

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