On-Chip Protein Biosynthesis

Authors

  • M. Sc. Christopher Timm,

    1. Karlsruhe Institute of Technology (KIT), Institute for Biological Interfaces (IBG 1), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen (Germany)
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  • Prof. Dr. Christof M. Niemeyer

    Corresponding author
    1. Karlsruhe Institute of Technology (KIT), Institute for Biological Interfaces (IBG 1), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen (Germany)
    • Karlsruhe Institute of Technology (KIT), Institute for Biological Interfaces (IBG 1), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen (Germany)
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Abstract

original image

Spot on! Cell-free protein expression on surfaces can be implemented in biosensors and in microfluidic devices like that shown in the picture. Proteins are generated and immobilized successively on separated spots in a microfluidic reactor. This approach opens up novel opportunities for basic and applied biomedical research.

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