We thank Mona Wolff and Anna-Maria Werner for excellent scientific support and Nina Bach and Katrin Lorenz-Baath for scientific discussions. S.A.S. was supported by the Deutsche Forschungsgemeinschaft SFB749, SFB1035, FOR1406, an ERC starting grant and the Center for Integrated Protein Science Munich CIPSM. T.W. thanks the TUM Graduate School for project funding. L.F.T. is thankful to the DFG, the VW-foundation, the State of Lower Saxony, and the Fonds der Chemischen Industrie for financial support.
The Two Faces of Potent Antitumor Duocarmycin-Based Drugs: A Structural Dissection Reveals Disparate Motifs for DNA versus Aldehyde Dehydrogenase 1 Affinity†
Article first published online: 16 MAY 2013
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 52, Issue 27, pages 6921–6925, July 1, 2013
How to Cite
Wirth, T., Pestel, G. F., Ganal, V., Kirmeier, T., Schuberth, I., Rein, T., Tietze, P. L. F. and Sieber, P. S. A. (2013), The Two Faces of Potent Antitumor Duocarmycin-Based Drugs: A Structural Dissection Reveals Disparate Motifs for DNA versus Aldehyde Dehydrogenase 1 Affinity . Angew. Chem. Int. Ed., 52: 6921–6925. doi: 10.1002/anie.201208941
- Issue published online: 21 JUN 2013
- Article first published online: 16 MAY 2013
- Manuscript Revised: 27 MAR 2013
- Manuscript Received: 8 NOV 2012
- Deutsche Forschungsgemeinschaft
- Center for Integrated Protein Science Munich CIPSM
- State of Lower Saxony
- Fonds der Chemischen Industrie
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