We thank Mona Wolff and Anna-Maria Werner for excellent scientific support and Nina Bach and Katrin Lorenz-Baath for scientific discussions. S.A.S. was supported by the Deutsche Forschungsgemeinschaft SFB749, SFB1035, FOR1406, an ERC starting grant and the Center for Integrated Protein Science Munich CIPSM. T.W. thanks the TUM Graduate School for project funding. L.F.T. is thankful to the DFG, the VW-foundation, the State of Lower Saxony, and the Fonds der Chemischen Industrie for financial support.
The Two Faces of Potent Antitumor Duocarmycin-Based Drugs: A Structural Dissection Reveals Disparate Motifs for DNA versus Aldehyde Dehydrogenase 1 Affinity†
Article first published online: 16 MAY 2013
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 52, Issue 27, pages 6921–6925, July 1, 2013
How to Cite
Wirth, T., Pestel, G. F., Ganal, V., Kirmeier, T., Schuberth, I., Rein, T., Tietze, P. L. F. and Sieber, P. S. A. (2013), The Two Faces of Potent Antitumor Duocarmycin-Based Drugs: A Structural Dissection Reveals Disparate Motifs for DNA versus Aldehyde Dehydrogenase 1 Affinity . Angew. Chem. Int. Ed., 52: 6921–6925. doi: 10.1002/anie.201208941
- Issue published online: 21 JUN 2013
- Article first published online: 16 MAY 2013
- Manuscript Revised: 27 MAR 2013
- Manuscript Received: 8 NOV 2012
- Deutsche Forschungsgemeinschaft
- Center for Integrated Protein Science Munich CIPSM
- State of Lower Saxony
- Fonds der Chemischen Industrie
As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Please note: Wiley Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.