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Keywords:

  • cell detachment;
  • host–guest systems;
  • stimuli responsive;
  • supramolecular chemistry
Thumbnail image of graphical abstract

Electrochemically activated cell release by using redox-active supramolecular complexes assembled on microelectrodes is described by P. Jonkheijm et al. in their Communication on page 12233 ff. Host molecule cucurbit[8]uril links surface-bound viologen to solution-exposed RGD peptides to form a cell-adhesive surface. Electrochemical reduction results in dissociation of the supramolecular complex, release of the RGD peptides, and detachment of cells from the surfaces.