Back Cover: A Supramolecular System for the Electrochemically Controlled Release of Cells (Angew. Chem. Int. Ed. 49/2012)

Authors

  • Dr. Qi An,

    1. Molecular Nanofabrication Group, Faculty of Science and Technology and MESA+Institute for Nanotechnology, University of Twente, P.O. Box 217, 7500 AE, Enschede (The Netherlands)
    2. Current address: National Laboratory of Mineral Materials, School of Materials Science and Technology, China University of Geosciences, No.29, Xueyuan Road, 100083, Beijing, P. R. China
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  • Jenny Brinkmann,

    1. Molecular Nanofabrication Group, Faculty of Science and Technology and MESA+Institute for Nanotechnology, University of Twente, P.O. Box 217, 7500 AE, Enschede (The Netherlands)
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  • Prof.Dr. Jurriaan Huskens,

    1. Molecular Nanofabrication Group, Faculty of Science and Technology and MESA+Institute for Nanotechnology, University of Twente, P.O. Box 217, 7500 AE, Enschede (The Netherlands)
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  • Sven Krabbenborg,

    1. Molecular Nanofabrication Group, Faculty of Science and Technology and MESA+Institute for Nanotechnology, University of Twente, P.O. Box 217, 7500 AE, Enschede (The Netherlands)
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  • Prof. Dr. Jan de Boer,

    1. MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, P.O. Box 217, 7500 AE, Enschede (The Netherlands)
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  • Dr. Pascal Jonkheijm

    Corresponding author
    1. Molecular Nanofabrication Group, Faculty of Science and Technology and MESA+Institute for Nanotechnology, University of Twente, P.O. Box 217, 7500 AE, Enschede (The Netherlands)
    • Molecular Nanofabrication Group, Faculty of Science and Technology and MESA+Institute for Nanotechnology, University of Twente, P.O. Box 217, 7500 AE, Enschede (The Netherlands)
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Abstract

original image

Electrochemically activated cell release by using redox-active supramolecular complexes assembled on microelectrodes is described by P. Jonkheijm et al. in their Communication on page 12233 ff. Host molecule cucurbit[8]uril links surface-bound viologen to solution-exposed RGD peptides to form a cell-adhesive surface. Electrochemical reduction results in dissociation of the supramolecular complex, release of the RGD peptides, and detachment of cells from the surfaces.

Cartoon 1.

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