The research leading to these results was partially funded by the European Research Council under the Seventh Framework Program of the European Union (FP7/2007-2013) and the ERC grant agreement No. 258593. The CNRS, the University of Strasbourg, and the icFRC are also acknowledged for financial support. We thank M. Legros, O. Gavat, and C. Foussat for the SEC measurements. P. Chaud and S. Pradeau are also acknowledged for their help in the preparation of azido sugars.
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Communication
Synthesis of Single-Chain Sugar Arrays†
Article first published online: 23 JAN 2013
DOI: 10.1002/anie.201209052
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Baradel, N., Fort, S., Halila, S., Badi, N. and Lutz, J.-F. (2013), Synthesis of Single-Chain Sugar Arrays . Angew. Chem. Int. Ed., 52: 2335–2339. doi: 10.1002/anie.201209052
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Publication History
- Issue published online: 13 FEB 2013
- Article first published online: 23 JAN 2013
- Manuscript Revised: 16 DEC 2012
- Manuscript Received: 12 NOV 2012
Funded by
- European Union. Grant Number: 258593
- CNRS
- University of Strasbourg
- icFRC
Keywords:
- biohybrid copolymers;
- glycopolymers;
- radical copolymerization;
- sequence-controlled polymers;
- single-chain arrays
Polymers that toe the line: Well-defined linear polystyrene chains containing precisely positioned hexose moieties (mannose, galactose, and N-acetylglucosamine) were synthesized by a sequence-controlled polymerization approach followed by a series of site-selective modification steps. Such multifunctional single-chain hexose arrays associate specifically with complementary lectins (see picture).