We acknowledge NSF support through use of the Cornell Nanofabrication Facility/NNIN and the Cornell Center for Materials Research facilities. J.A.M. gratefully acknowledges the Integrative Graduate Education and Research Traineeship (IGERT) Program in the Nanoscale Control of Surfaces and Interfaces, which is supported under NSF Award DGE-0654193, the Cornell Center for Materials Research, and Cornell University. T.A. acknowledges funding through a grant from the National Science Foundation under ECCS-1001742 and through support from Analog Devices.
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Communication
Preservation of Antibody Selectivity on Graphene by Conjugation to a Tripod Monolayer†
Article first published online: 5 FEB 2013
DOI: 10.1002/anie.201209149
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Mann, J. A., Alava, T., Craighead, H. G. and Dichtel, W. R. (2013), Preservation of Antibody Selectivity on Graphene by Conjugation to a Tripod Monolayer . Angew. Chem. Int. Ed., 52: 3177–3180. doi: 10.1002/anie.201209149
- †
Publication History
- Issue published online: 7 MAR 2013
- Article first published online: 5 FEB 2013
- Manuscript Received: 15 NOV 2012
Funded by
- NSF. Grant Number: DGE-0654193
- Cornell Center for Materials Research
- Cornell University
- National Science Foundation. Grant Number: ECCS-1001742
Keywords:
- antibodies;
- biofunctionalization;
- graphene;
- self-assembly
Three is a magic number: Antibodies adsorbed on bare graphene lose their ability to recognize antigens. However, this obstacle can be overcome by the conjugation of these antibodies to self-assembled monolayers of a tripodal compound (see picture).