We gratefully acknowledge Prof. Dr. H. Waldmann for his generous support.
Direct Selective Oxidative Cross-Coupling of Simple Alkanes with Heteroarenes†
Article first published online: 31 JAN 2013
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 52, Issue 11, pages 3267–3271, March 11, 2013
How to Cite
Antonchick, A. P. and Burgmann, L. (2013), Direct Selective Oxidative Cross-Coupling of Simple Alkanes with Heteroarenes. Angew. Chem. Int. Ed., 52: 3267–3271. doi: 10.1002/anie.201209584
- Issue published online: 7 MAR 2013
- Article first published online: 31 JAN 2013
- Manuscript Received: 29 NOV 2012
- hypervalent iodine;
A dream reaction: An efficient and practical method for the oxidative cross-coupling of heteroaromatic compounds and simple alkanes has been developed. The desired products are smoothly and regioselectively formed under mild reaction conditions at ambient temperature in a hypervalent-iodine-mediated transformation. The method allows for preferential transformation of stronger CH bonds in the presence of weaker CH bonds under metal-free conditions.