We gratefully acknowledge financial support from MICINN of Spain (grant CTQ2010-16790), MEC (FPU-predoctoral grants to A.G. and J.C.).
Catalytic Generation and Selective Heterocoupling of Two Electron-Rich Alkenes†
Article first published online: 25 APR 2013
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 52, Issue 23, pages 6038–6042, June 3, 2013
How to Cite
Galván, A., Calleja, J., Fañanás, F. J. and Rodríguez, F. (2013), Catalytic Generation and Selective Heterocoupling of Two Electron-Rich Alkenes . Angew. Chem. Int. Ed., 52: 6038–6042. doi: 10.1002/anie.201209870
- Issue published online: 30 MAY 2013
- Article first published online: 25 APR 2013
- Manuscript Revised: 19 MAR 2013
- Manuscript Received: 10 DEC 2012
- MICINN of Spain. Grant Number: CTQ2010-16790
- cascade reactions;
- homogeneous catalysis;
Complex heterocyclic products were synthesized from simple alkynamine and alkynol derivatives in a double cycloisomerization/heterodimerization cascade reaction (see scheme). The reaction includes the heterocoupling reaction of two different electron-rich alkenes and leads to the formation of four new bonds and three stereocenters (two of them quaternary).