Direct Access to Benzo[b]furans through Palladium-Catalyzed Oxidative Annulation of Phenols and Unactivated Internal Alkynes


  • We thank the CSIR, INDIA, the University of Hyderabad, and ACRHEM for financial support. M.R.K. and M.B. thank CSIR, India for fellowship. Support of R. Kishore, C. C. Gupta, and Dr. P. Raghavaiah for the X-ray crystallographic analysis is appreciated.


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2,3-Disubstituted benzo[b]furans are prepared in one step from commercially available phenols and readily accessible unactivated internal alkynes (see scheme). This Pd-catalyzed oxidative annulation has a broad substrate scope and allows access to a wide range of benzo[b]furans.