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Keywords:

  • block copolymers;
  • glycosylation;
  • polymerization;
  • polymers;
  • supramolecular chemistry
Thumbnail image of graphical abstract

Chain of command: Multi-block glycopolymers made of mannose (M, see figure), glucose, and di(ethylene glycol) ethyl ether (D) monomers were synthesized using a technique to control the polymer sequence. These highly monodisperse glycopolymers were then tested for binding and inhibition of DC-SIGN, a protein important for HIV infection.