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Keywords:

  • heme binding;
  • membrane-peptide mimetics;
  • NMR spectroscopy;
  • peptides;
  • peroxidases
Thumbnail image of graphical abstract

Autonomously folded designed β-hairpin peptides in detergent micelles show peroxidase activity with heme binding. Aromatic–aromatic cross-strand packing interactions that stabilize β-hairpin structures in solution are not strictly required for the structure and activity of a β-hairpin folded in a micelle environment.