Acceptorless Dehydrogenation of Nitrogen Heterocycles with a Versatile Iridium Catalyst


  • We thank the EPSRC and the University of Liverpool for a DTA studentship, Dr. Weijun Tang, Yi Zhang, and Dr. Jonathan H. Barnard for assistance and the EPSRC NMSSC at Swansea University for mass analysis.


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Gas up: A cyclometalated iridium complex is found to catalyze the dehydrogenation of various benzofused N-heterocycles, thus releasing H2. Driven by as low as 0.1 mol % catalyst, the reaction affords quinolines, indoles, quinoxalines, isoquinolines, and β-carbolines in high yields.