SEARCH

SEARCH BY CITATION

Keywords:

  • chemotherapy;
  • doxorubicin;
  • drug delivery;
  • nanoparticles;
  • zinc oxide
Thumbnail image of graphical abstract

Luminescent ZnO@polymer core–shell nanoparticles were synthesized and loaded with doxorubicin (DOX) for the treatment of human brain cancer cells. Analyses by confocal laser scanning microscopy proved that the ZnO@polymer–DOX nanocomposites were decomposed at lysosomes to release DOX molecules, which penetrated into the nucleus and finally killed the cells (see picture).