Inside Cover: Asbestos-like Pathogenicity of Long Carbon Nanotubes Alleviated by Chemical Functionalization (Angew. Chem. Int. Ed. 8/2013)

Authors

  • Dr. Hanene Ali-Boucetta,

    1. Nanomedicine Laboratory, UCL School of Pharmacy, University College London, Brunswick Square, London WC1N 1AX (UK)
    2. Current address: Pharmacy, Pharmacology and Therapeutics, School of Experimental and Clinical Medicine, Medical School, University of Birmingham, Birmingham B15 2TT (UK)
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  • Dr. Antonio Nunes,

    1. Nanomedicine Laboratory, UCL School of Pharmacy, University College London, Brunswick Square, London WC1N 1AX (UK)
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  • Dr. Raquel Sainz,

    1. CNRS, Institut de Biologie Moléculaire et Cellulaire, Laboratoire d'Immunopathologie et Chimie Thérapeutique, 67000 Strasbourg (France)
    2. Current address: NanoInnova Technologies SL, Parque Científico de Madrid, Madrid (Spain)
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  • Dr.  M. Antonia Herrero,

    1. Departamento de Química Orgánica, Facultad de Química, Universidad de Castilla-La Mancha, 13071 Ciudad Real (Spain)
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  • Dr. Bowen Tian,

    1. Nanomedicine Laboratory, UCL School of Pharmacy, University College London, Brunswick Square, London WC1N 1AX (UK)
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  • Prof. Maurizio Prato,

    Corresponding author
    1. Dipartimento di Scienze Farmaceutiche, Università di Trieste, 34127 Trieste (Italy)
    • Maurizio Prato, Dipartimento di Scienze Farmaceutiche, Università di Trieste, 34127 Trieste (Italy)===

      Alberto Bianco, CNRS, Institut de Biologie Moléculaire et Cellulaire, Laboratoire d'Immunopathologie et Chimie Thérapeutique, 67000 Strasbourg (France)===

      Kostas Kostarelos, Nanomedicine Laboratory, UCL School of Pharmacy, University College London, Brunswick Square, London WC1N 1AX (UK)===

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  • Dr. Alberto Bianco,

    Corresponding author
    1. CNRS, Institut de Biologie Moléculaire et Cellulaire, Laboratoire d'Immunopathologie et Chimie Thérapeutique, 67000 Strasbourg (France)
    • Maurizio Prato, Dipartimento di Scienze Farmaceutiche, Università di Trieste, 34127 Trieste (Italy)===

      Alberto Bianco, CNRS, Institut de Biologie Moléculaire et Cellulaire, Laboratoire d'Immunopathologie et Chimie Thérapeutique, 67000 Strasbourg (France)===

      Kostas Kostarelos, Nanomedicine Laboratory, UCL School of Pharmacy, University College London, Brunswick Square, London WC1N 1AX (UK)===

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  • Prof. Kostas Kostarelos

    Corresponding author
    1. Nanomedicine Laboratory, UCL School of Pharmacy, University College London, Brunswick Square, London WC1N 1AX (UK)
    • Maurizio Prato, Dipartimento di Scienze Farmaceutiche, Università di Trieste, 34127 Trieste (Italy)===

      Alberto Bianco, CNRS, Institut de Biologie Moléculaire et Cellulaire, Laboratoire d'Immunopathologie et Chimie Thérapeutique, 67000 Strasbourg (France)===

      Kostas Kostarelos, Nanomedicine Laboratory, UCL School of Pharmacy, University College London, Brunswick Square, London WC1N 1AX (UK)===

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Abstract

original image

Alleviation of the asbestos-like pathogenicity of long, pristine carbon nanotubes is possible by modifying their surface and reducing their effective length by de-bundling, following certain types of chemical functionalization. In their Communication on page 2274 ff., M. Prato, A. Bianco, K. Kostarelos, et al. show that a 1,3-dipolar cycloaddition reaction on carbon nanotubes produces well-dispersed individualized nanotubes with a risk-free toxicity profile.

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