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Selective Palladium-Catalyzed Hydroformylation of Alkynes to α,β-Unsaturated Aldehydes


  • This research was funded by Evonik Industries, Advanced Intermediates, Performance Intermediates, and the Deutsche Forschungsgemeinschaft (Leibniz Prize to M.B.). We thank Dr. C. Fisher, S. Buchholz, and S. Schareina for their excellent technical and analytical support.


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Atom-efficient: A selective palladium catalyst system is used for the hydroformylation of alkynes (see picture). In this syngas reaction, various alkynes were smoothly transformed to synthetically interesting α,β-unsaturated aldehydes in good yields with high regio- and stereoselectivity.