Cover Picture: Palladium-Catalyzed Oxidative Cross-Coupling between Heterocycles and Terminal Alkynes with Low Catalyst Loading (Angew. Chem. Int. Ed. 13/2013)

Authors

  • Dr. Xiaoming Jie,

    1. State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Yangqiao west road 155#, Fuzhou, Fujian 350002 (China)
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  • Yaping Shang,

    1. State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Yangqiao west road 155#, Fuzhou, Fujian 350002 (China)
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  • Peng Hu,

    1. State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Yangqiao west road 155#, Fuzhou, Fujian 350002 (China)
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  • Prof. Dr. Weiping Su

    Corresponding author
    1. State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Yangqiao west road 155#, Fuzhou, Fujian 350002 (China)
    • State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Yangqiao west road 155#, Fuzhou, Fujian 350002 (China)===

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Abstract

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The direct alkynylation of electron-rich aromatic heterocycles with terminal alkynes was accomplished in high yields and good selectivity when using a low loading of palladium catalyst, as described by W. Su and co-workers in their Communication on page 3630 ff. A high loading of palladium catalyst led to poor yields because of the undesired homocoupling of alkynes.

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