SEARCH

SEARCH BY CITATION

Keywords:

  • click chemistry;
  • energy transfer;
  • fluorescent probes;
  • fluorogenic probes;
  • tetrazines
Thumbnail image of graphical abstract

The fastest and the brightest: A new design that intimately connects tetrazine to a BODIPY fluorophore enables exceptionally efficient energy transfer and quenching. Upon reaction of the tetrazine, the brightness of the fluorophore increases more than a thousand-fold, which is a fluorogenic activation up to two orders of magnitude greater than previously described.