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A Programmable Sensor to Probe the Internalization of Proteins and Nanoparticles in Live Cells

Authors

  • Haiyin Liu,

    1. Nanomaterials for Biology Group, Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Melbourne, 3010 (Australia)
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  • Dr. Angus P. R. Johnston

    Corresponding author
    1. Nanomaterials for Biology Group, Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Melbourne, 3010 (Australia)
    • Nanomaterials for Biology Group, Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Melbourne, 3010 (Australia)

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  • This work was supported through the ARC Future Fellowship Scheme (A.P.R.J.).

Abstract

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A molecular sensor has been developed to probe the internalization of proteins and nanoparticles into live cells. This simple, high-throughput technique is compatible with cell phenotyping and is independent of the cellular fate of the material.

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