Cover Picture: Protection and Deprotection of DNA—High-Temperature Stability of Nucleic Acid Barcodes for Polymer Labeling (Angew. Chem. Int. Ed. 15/2013)
Article first published online: 13 MAR 2013
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 52, Issue 15, page 4041, April 8, 2013
How to Cite
Paunescu, D., Fuhrer, R. and Grass, R. N. (2013), Cover Picture: Protection and Deprotection of DNA—High-Temperature Stability of Nucleic Acid Barcodes for Polymer Labeling (Angew. Chem. Int. Ed. 15/2013). Angew. Chem. Int. Ed., 52: 4041. doi: 10.1002/anie.201301653
- Issue published online: 3 APR 2013
- Article first published online: 13 MAR 2013
- polymerase chain reaction;
- sol–gel processes
When DNA is encapsulated in a silica sphere, the encoded information can be protected for storage and distribution, much in the way a bottle protects the message inside from the rough sea. As R. N. Grass et al. describe in their Communication on page 4269 ff., a silica layer only 10 nm thick is sufficient to protect DNA from high temperatures and aggressive radical conditions. The glass can be broken by reaction with HF and the information recovered for biochemical analysis.
A new class of ketosynthases (DarB) involved in the biosynthesis of 1,3-cyclohexanediones and dialkylresorcinols has been identified by H. B. Bode and co-workers, as reported in their Communication on page 4108 ff.. Picture: Tim Schöner.
In their Communication on page 4174 ff., K. Sada et al. present facile control of lower critical solution temperature behavior of an organic polymer by manipulating charge-transfer interactions between the polymer and an effector‥
B. Åkermark and co-workers present in their Communication on page 4189 ff., a previously undiscovered deactivation pathway for ruthenium-based water oxidation catalysts.