Get access

Noncovalent Interactions in Organocatalysis: Modulating Conformational Diversity and Reactivity in the MacMillan Catalyst

Authors


  • We acknowledge generous financial support from the WWU Münster, the DFG (SFB 749), and the ETH Zürich (ETH Independent Investigator Research Award to R.G.).

Abstract

original image

Intriguing imidazolidinones! Inspired by noncovalent interactions in proteins, a series of electronically distinct MacMillan catalysts were designed. The effect of electronic modulation on ground state conformation, reactivity, and performance was studied in a catalytic setting with intriguing outcomes.

Get access to the full text of this article

Ancillary