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The Structural Basis of G-Protein-Coupled Receptor Signaling (Nobel Lecture)

Authors

  • Prof. Brian Kobilka

    Corresponding author
    1. Stanford University School of Medicine, Department of Molecular and Cellular Physiology, 279 Campus Drive, Stanford, CA 94305 (USA)
    • Stanford University School of Medicine, Department of Molecular and Cellular Physiology, 279 Campus Drive, Stanford, CA 94305 (USA)

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  • Copyright© The Nobel Foundation 2012. We thank the Nobel Foundation, Stockholm, for permission to print this lecture.

Abstract

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Cells from different parts of our bodies communicate with each other using chemical messengers in the form of hormones and neurotransmitters. They process information encoded in these chemical messages using G-protein-coupled receptors (GPCRs) located in the plasma membrane. The Nobel Prize for Chemistry 2012 was awarded for studies on GPCRs.

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