Get access

Thermostable Branched DNA Nanostructures as Modular Primers for Polymerase Chain Reaction


  • We acknowledge support from USDA NE-SARE, USDA AFRI, Bill & Melinda Gates Foundation, and NY Center for Advanced Materials Processing.


original image

Chemical cross-linking was used to prepare DNA nanostructures with enhanced thermal stability. These thermostable DNA nanostructures were then utilized as modular primers in the polymerase chain reaction (PCR; see picture), thus enabling the production of multifunctionalized and branched PCR products for multiplexed detection and hydrogel formation.

Get access to the full text of this article