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Keywords:

  • alginate;
  • hydrogels;
  • mechanical stimulation;
  • microfluidics;
  • polydimethylsiloxanes
Thumbnail image of graphical abstract

Hydrogel meets silicone: The chemical functionalization of a polydimethylsiloxane (PDMS) surface with polysaccharide “glue” induces a strong, permanent adhesion between the hydrogel and PDMS. This hydrogel-coated silicone substrate was useful for controlling cellular organization under mechanical stretching (see picture) and also in fabricating microfluidic devices filled with the gel.