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Keywords:

  • alkynes;
  • amides;
  • C[BOND]C bond cleavage;
  • gold;
  • rearrangement
Thumbnail image of graphical abstract

Breakthrough: A novel catalyzed direct highly selective Cmath image[BOND]Csp bond functionalization of alkynes to amides has been developed. Nitrogenation is achieved by the highly selective Cmath image[BOND]Csp bond cleavage of aryl-substituted alkynes. The oxidant-free and mild conditions and wide substrate scope make this method very practical.