Cover Picture: Exploring the Mechanism of IR–UV Double-Resonance for Quantitative Spectroscopy of Protonated Polypeptides and Proteins (Angew. Chem. Int. Ed. 23/2013)

Authors


Abstract

original image

Determination of the 3D structures … of large molecules challenges spectroscopy to perform better. In their Communication on page 6002 ff. O. V. Boyarkin et al. use IR–UV double-resonance cold-ion spectroscopy for conformational assignment of the electronic spectra of a protonated decapeptide and for measurements of absolute absorption cross-sections of vibrational transitions in this species. The limitations of the IR–UV double-resonance approach are illustrated by measuring the gas-phase IR spectrum of a cold, protonated intact protein.

Ancillary