Cover Picture: Regioselectively Functionalized Pyridines from Sustainable Resources (Angew. Chem. Int. Ed. 24/2013)



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In the sustainable Ir-catalyzed synthesis of pyridine derivatives described by R. Kempe and S. Michlik in their Communication on page 6326 ff., alcohols and 1,3-amino alcohols are deoxygenated and selectively linked in C[BOND]N and C[BOND]C bond-forming steps. Three equivalents of hydrogen gas are liberated per generated pyridine unit (see reaction scheme). The wood and blossums in the background underline the fact that the starting materials can be obtained from renewable resources.