Simple and Green Synthesis of Nitrogen-Doped Photoluminescent Carbonaceous Nanospheres for Bioimaging


  • This work was supported by the State Key Basic Research Program of the PRC (2012CB224805, 2013CB934104), and the NSF of China (21210004).


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From silk to spheres: A large-scale synthesis of water-soluble nitrogen-doped polymer-like carbonaceous nanospheres with a uniform size of ca. 70 nm, through a simple and green hydrothermal process employing cocoon silk in water, has been developed. The resultant nanospheres show excellent photoluminescent properties, exhibit low toxicity, and are biocompatible for in vivo imaging.