The authors gratefully acknowledge Sven Hausner and Kevin Lau for their assistance with experimental design. This work was supported by an NIH grant (C4EB012836-01) to J.S. and an NSF EFRI grant (0937997) to A.R.
Micropatterned Photodegradable Hydrogels for the Sorting of Microbeads and Cells†
Article first published online: 19 JUL 2013
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 52, Issue 35, pages 9224–9228, August 26, 2013
How to Cite
Siltanen, C., Shin, D.-S., Sutcliffe, J. and Revzin, A. (2013), Micropatterned Photodegradable Hydrogels for the Sorting of Microbeads and Cells . Angew. Chem. Int. Ed., 52: 9224–9228. doi: 10.1002/anie.201303965
- Issue published online: 22 AUG 2013
- Article first published online: 19 JUL 2013
- Manuscript Received: 9 MAY 2013
- cell sorting;
- soft lithography
Sorted out: Soft-lithography micropatterning of a photodegradable poly(ethylene glycol) hydrogel was utilized to sort cell-bound microbeads. Biofunctionalized microbeads were patterned, screened for cell binding activity, and isolated from arrays by UV irradiation. The technique is a simple approach for sorting and downstream processing of cultured cells.