These authors contributed equally to this work.
Back Cover: The Fatty Acid Composition of Diacylglycerols Determines Local Signaling Patterns (Angew. Chem. Int. Ed. 24/2013)
Article first published online: 31 MAY 2013
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 52, Issue 24, page 6340, June 10, 2013
How to Cite
Nadler, A., Reither, G., Feng, S., Stein, F., Reither, S., Müller, R. and Schultz, C. (2013), Back Cover: The Fatty Acid Composition of Diacylglycerols Determines Local Signaling Patterns (Angew. Chem. Int. Ed. 24/2013). Angew. Chem. Int. Ed., 52: 6340. doi: 10.1002/anie.201304203
- Issue published online: 5 JUN 2013
- Article first published online: 31 MAY 2013
- caged lipids;
- fatty acid composition;
- protein kinase C;
- signaling networks
Photoactivatable or “caged” derivatives of signaling molecules are important tools for manipulating intracellular events with spatial and temporal resolution. In their Communication on page 6330 ff., C. Schultz and co-workers demonstrate that regionally limited photoactivation simultaneously leads to a local protein kinase C and a global calcium response. Surprisingly, the orchestration of these effects seems to depend on the fatty acid composition of the released lipid.