The project is supported by the National Basic Research Program of China (973 Program, No. 2009CB825300), Natural Science Foundation of China (Grant No. 21272010, 21262023), and the Program for Young Talents of Science and Technology in Universities of Inner Mongolia Autonomous Region (NJYT-12-B03).
Palladium-Catalyzed Three-Component Reaction of Allenes, Aryl Iodides, and Diazo Compounds: Approach to 1,3-Dienes†
Article first published online: 15 JUL 2013
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 52, Issue 35, pages 9305–9308, August 26, 2013
How to Cite
Xiao, Q., Wang, B., Tian, L., Yang, Y., Ma, J., Zhang, Y., Chen, S. and Wang, J. (2013), Palladium-Catalyzed Three-Component Reaction of Allenes, Aryl Iodides, and Diazo Compounds: Approach to 1,3-Dienes . Angew. Chem. Int. Ed., 52: 9305–9308. doi: 10.1002/anie.201304327
- Issue published online: 22 AUG 2013
- Article first published online: 15 JUL 2013
- Manuscript Received: 20 MAY 2013
- National Basic Research Program of China. Grant Number: 2009CB825300
- Natural Science Foundation of China. Grant Numbers: 21272010, 21262023
- diazo compounds;
- multicomponent reactions
'Diene' to know: The title reaction leads to the formation of 1,3-dienes in high yields (see scheme). The reaction also proceeds with the use of N-tosylhydrazone substrates. Carbopalladation to the allene and palladium carbene migratory insertion are proposed to play the key role in this transformation.